What is the function of glucagon?

Prepare for the Anatomy and Physiology Test. Use flashcards and multiple choice questions, each with hints. Enhance your knowledge for the exam of the multiple organ systems!

Multiple Choice

What is the function of glucagon?

Explanation:
Glucagon raises blood glucose by signaling the liver to release glucose when levels are low. It’s released from pancreatic alpha cells in response to falling blood sugar and acts mainly on liver cells. By binding to its receptors, it increases cAMP inside hepatocytes, which activates pathways for glycogenolysis (breaking down stored glycogen into glucose) and gluconeogenesis (making new glucose from non-carbohydrate sources). The net result is more glucose released into the bloodstream. This is opposite to insulin, which lowers blood glucose. The other options describe functions unrelated to glucagon—decreasing glucose, regulating melatonin, or promoting urine formation—so they don’t fit the hormone’s role.

Glucagon raises blood glucose by signaling the liver to release glucose when levels are low. It’s released from pancreatic alpha cells in response to falling blood sugar and acts mainly on liver cells. By binding to its receptors, it increases cAMP inside hepatocytes, which activates pathways for glycogenolysis (breaking down stored glycogen into glucose) and gluconeogenesis (making new glucose from non-carbohydrate sources). The net result is more glucose released into the bloodstream. This is opposite to insulin, which lowers blood glucose. The other options describe functions unrelated to glucagon—decreasing glucose, regulating melatonin, or promoting urine formation—so they don’t fit the hormone’s role.

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