Which statement about progesterone's role is true?

Which statement about progesterone's role is true?

• A. Progesterone stimulates ovulation
• B. Progesterone is produced by the ovaries
• C. Progesterone causes endometrial shedding
• D. Progesterone prepares endometrium for implantation, myometrial contractions

Answer: (D)

Progesterone after ovulation reshapes the endometrium into a secretory, nutrient-rich lining that can support an early embryo. It also keeps the uterus in a quiescent state by dampening myometrial contractions, which helps implantation occur without being disrupted by strong uterine squeezes. This combination—making the endometrium receptive and reducing contractions—is why the statement about preparing the endometrium for implantation and modulating uterine activity is true. Ovulation is driven by LH, not progesterone, so progesterone does not stimulate ovulation. Progesterone is produced by the ovaries (and later by the placenta during pregnancy), but its defining role in this context is its effect on the endometrium and uterine tone to favor implantation.

Progesterone after ovulation reshapes the endometrium into a secretory, nutrient-rich lining that can support an early embryo. It also keeps the uterus in a quiescent state by dampening myometrial contractions, which helps implantation occur without being disrupted by strong uterine squeezes. This combination—making the endometrium receptive and reducing contractions—is why the statement about preparing the endometrium for implantation and modulating uterine activity is true. Ovulation is driven by LH, not progesterone, so progesterone does not stimulate ovulation. Progesterone is produced by the ovaries (and later by the placenta during pregnancy), but its defining role in this context is its effect on the endometrium and uterine tone to favor implantation.